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Featured Studies

This web page makes it easy to search for featured research studies at the NIH Clinical Center. You can search for specific studies by entering keywords related to your symptoms in the search box or by using the sort and filter options.


To view a full list of all studies conducted at the NIH Clinical Center, visit Search the Studies.

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24 results
Nicotinamide Riboside and Ketone Metabolism

Nicotinamide Riboside and Ketone Metabolism

Dr. Kevin Hall and his team at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) are seeking male volunteers aged 18-65 and female volunteers aged 18-50 for a study on how low-carb (ketogenic) diets, with or without an investigational dietary supplement called Nicotinamide Riboside, impacts energy levels and metabolism during sleep.
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Natural History Study of CADASIL

Natural History Study of CADASIL

Researchers are examining genetic and physical characteristics of the small vessel disease called CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy). They are enrolling volunteers to serve as healthy controls. Compensation is provided.
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A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Intravenous ZMA001 in Healthy Subjects

A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Intravenous ZMA001 in Healthy Subjects

Healthy volunteers 18-60 years old are needed to test an investigational drug that was developed to reduce blood pressure in the lungs. The PAH team from @NHLBI hope that this investigational study drug may be helpful in treating patients with PAH in the future.
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A Study of Anti-Cancer Drug Abemaciclib on Brain Tumors

A Study of Anti-Cancer Drug Abemaciclib on Brain Tumors

Researchers want to see if they can measure the amount of anti-cancer drug, Abemaciclib in a brain tumor and brain fluid after a patient has taken this drug for a few days. These findings can help explain how much drug gets into the brain and how drugs work to shrink high grade gliomas to improve outcomes for these patients.
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Dive into How Processed Foods Affect Your Health!

Dive into How Processed Foods Affect Your Health!

Diets worldwide include both processed and unprocessed foods. Researchers at the National Institutes of Health (NIH) in Bethesda, Maryland seek adult volunteers between 18-60 years old to participate in a study examining how processed and unprocessed foods affect metabolic health. Participants will be required to remain at the NIH Clinical Center for one 4-week stay and eat only the foods provided.

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NIH Tests Fecal Transplant in Chronic Granulomatous Disease-Associated Colitis

NIH Tests Fecal Transplant in Chronic Granulomatous Disease-Associated Colitis

Researchers at NIH are testing a new therapy in patients diagnosed with colitis due to chronic granulomatous disease (CGD). The research aims to see if restoring the gut microbiome reduces inflammation in the colon.

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Energy Expenditure Responses to Different Temperatures

Energy Expenditure Responses to Different Temperatures

Researchers at the National Institutes of Health (NIH) Clinical Center seek healthy women to participate in a research study. Doctors want to learn how the body burns energy at different temperatures. Compensation is provided.
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