Do You or Your Child Have Colitis Related to Chronic Granulomatous Disease?
Chronic granulomatous disease (CGD) is an inherited genetic disorder associated with inflammation of the intestines (colitis). This may be due to disruption of the gut's good bacteria (microbiome). Researchers at the National Institutes of Health (NIH) are testing the placing of good bacteria from donor stool into the intestine of a person with CGD (called fecal microbiota transplantation, or FMT) for its ability to restore the gut microbiome and treat CGD colitis.
Eligible participants:
- Are ages 10 to 60 years diagnosed with CGD and colitis
Study Involves:
- An initial screening visit (in-person or virtual) for medical history and CGD questionnaires
- At-home stool collections
- If eligible, a 3-day overnight stay at the NIH Clinical Center for FMT
- After treatment, follow-up visits (in-person or virtual)
Study-related tests and treatments are at no cost. Travel assistance may be provided, and onsite parking is available.
To learn more, call:
NIH Clinical Center Office of Patient Recruitment
800-411-1222
(TTY users dial 7-1-1)
Email: ccopr@nih.gov
Or go online:
https://go.usa.gov/xJCg3
Refer to study #000809-I
Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Institute of Allergy and Infectious Diseases (NIAID)