Featured Studies

Researchers are examining genetic and physical characteristics of the small vessel disease called CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy). They are enrolling volunteers to serve as healthy controls. Compensation is provided.

Healthy volunteers 18-60 years old are needed to test an investigational drug that was developed to reduce blood pressure in the lungs. The PAH team from @NHLBI hope that this investigational study drug may be helpful in treating patients with PAH in the future.

Myelodysplastic syndromes (MDS) are disorders caused by abnormal blood cell production, potentially leading to low cell counts and increased susceptibility to clotting and infections. Past research suggests that inflammation may trigger these abnormalities, and this study seeks to further understand and improve treatment strategies for MDS by investigating the role of inflammation in bone marrow cell development.

This study aims to learn more about how drinking alcohol changes your decision-making. Participants will be asked to consume drinks that might or might not have alcohol, then have magnetic resonance imaging (MRI) scans to look at brain activity while making choices related to risky sexual behavior. The study requires two visits to the NIH Clinical Center. Compensation of up to $400 for your time and effort will be provided.

Malaria is a dangerous disease that impacts hundreds of millions of people in Africa, Asia, and Latin America. It can cause severe disease and even death. Researchers at NIH's Laboratory of Malaria Immunology and Vaccinology are seeking healthy volunteers to be part of a malaria vaccine research study.

A research study at the National Institutes of Health (NIH) is is investigating how dietary habits affect our intestinal microorganisms by studying the effects of Mediterranean-like unprocessed (CLEAN-MED) diet. Participants will be divided into two groups, depending on their interest in trying out the diet for 4 weeks or maintaining a new healthy diet over months, and will be provided with some foods. Participants will log the food they eat and answer questions about their diet throughtout the study. Food and research supplies and procedures are provided at no cost.

Do you... Find yourself constantly checking things? Spend lots of time ordering your belongings? Have unusual rituals or habits that seem unnecessary? Do you blurt out comments at inappropriate times, interrupt conversations or speak out of turn or feel you are overly impulsive? The National Human Genome Research Institute (NHGRI) is conducting an outpatient research study on the links between compulsivity, impulsivity and the developing brain in children and young adults.

People with systemic lupus erythematosus (SLE) are at risk of developing complications in their blood vessels. The risks increase for heart attacks or stroke. No medications have been effective at reducing this risk in people with lupus. Researchers at NIH are testing whether a drug (anifrolumab) can improve blood vessel function and reduce blood vessel inflammation in people with (SLE). Participants do not pay for tests, treatments, or procedures.

Doctors at the National Institutes of Health (NIH) are conducting a research study to determine the viability and safety of early initiation of oral therapy with cyclosporine and eltrombopag in patients with severe aplastic anemia (SAA).