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Featured Studies

This web page is designed to make it easy to search the NIH Clinical Center's research studies. You may search for specific studies matching your symptoms using key words in the search box or sort/filter the study results.

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135 results
Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease

Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease

Doctors at the National Institutes of Health (NIH) seek healthy volunteers (with or without a sickle cell trait) and patients with sickle cell for a research study. Sickle cell disease is a genetic blood disorder that occurs mainly in people of African descent. Study participants will have a one-time visit to the NIH to provide blood samples. Researchers hope this study will help us better understand sickle cell disease.
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Men at High Genetic Risk for Prostate Cancer

Men at High Genetic Risk for Prostate Cancer

Join a National Institutes of Health (NIH) research study seeking mean men who have a genetic risk factor for developing prostate cancer. Researchers want to follow the prostate health of men who have specific genetic changes associated with prostate cancer to help them learn more about which men are at higher risk for prostate cancer.
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An Open-Label Phase 3 Study of the Safety and Efficacy of Pegvisomant in Children with Growth Hormone Excess

An Open-Label Phase 3 Study of the Safety and Efficacy of Pegvisomant in Children with Growth Hormone Excess

Gigantism is a condition characterized by excessive growth and height significantly above average, caused by over-production of growth hormone (GH) during childhood. Investigators at the National Institutes of Health (NIH) want to see if a drug that antagonizes growth hormone action, called pegvisomant, can help children and adolescents with gigantism.
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Non-Alcoholic Fatty Liver Disease, the Hepatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)

Non-Alcoholic Fatty Liver Disease, the Hepatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES) (En español)

Are you looking for a treatment for non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH)? Researchers at the National Institutes of Health (NIH) seek volunteers to participate in a research study. For 30 weeks, participants will receive a medication called semaglutide (typically used for Type 2 diabetes), aiming to improve their liver disease and help them lose weight. The study hopes to better understand liver damage and its treatment in people with these conditions. (En español)
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Hígado graso no alcohólico, respuesta hepática a la glucosa oral y efecto de la semaglutida (NAFLD HEROES)

Hígado graso no alcohólico, respuesta hepática a la glucosa oral y efecto de la semaglutida (NAFLD HEROES)

¿Está buscando un tratamiento para su condición de hígado graso no alcohólico (NAFLD, por sus siglas en inglés) o para la esteatohepatitis no alcohólica (NASH, por sus siglas en inglés)? Investigadores de los Institutos Nacionales de la Salud, buscan voluntarios para participar en este estudio. Por 30 semanas, los participantes recibirán semaglutide (medicina usada para la diabetes tipo 2), esto podría mejorar su hígado y ayudarle a perder peso. El estudio espera entender mejor el daño del hígado y los mejores tratamientos para las personas con estas condiciones.
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Pilot Study for Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Pilot Study for Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Does your pace of life in the city affect your health? Researchers at the National Institutes of Health (NIH) are conducting a study of two neighborhoods in Washington, D.C. in relationship to the environmental stress and the health behaviors of White and African American women. This research study will work to determine if there is a significant connection between neighborhood environment and the impact in women's health.
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Viral Load in Blood and Lymph Tissues of HIV-Infected Individuals

Viral Load in Blood and Lymph Tissues of HIV-Infected Individuals

Doctors at the National Institutes of Health are conducting a research study (92-I-0125) to learn more about the immune system and how it responds to HIV infection in blood, lymph nodes, and bone marrow. We are seeking healthy volunteers to have a lymph node biopsy to compare with patients who have HIV.
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Study of Systemic Lupus Erythematosus

Study of Systemic Lupus Erythematosus

The National Institutes of Health (NIH) is conducting a research study for patients with lupus. Doctors want to learn more about the disease and are looking for what causes it, how it progresses over time, and the genetic factors that might make a person more likely to develop it. This study is open to any individual, 10 years of age or older, who meets the American College of Rheumatology's criteria for having lupus, which include symptoms and abnormal blood tests.

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Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes

Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes

Doctors at the National Institutes of Health (NIH) are investigating new techniques needed to develop gene therapy or other treatment for certain inherited immune system diseases. If you have an inherited disease that is affecting your blood or bone marrow cell that generate blood cells, you may be eligible to participate in this research study. Participants will be screened with a medical history, physical examination and blood and urine tests.

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