Featured Studies

Researchers at the National Heart, Lung, and Blood Institute in Bethesda, Maryland, are conducting a study to evaluate the airway immunity in adults with a positive TB skin or blood test. With this study, researchers hope to discover better prevention and treatments for TB.

Systemic lupus erythematosus (SLE) creates an imbalance in the innate immune system responsible for chronic inflammation. A study at NHLBI is looking into a Vitamin B supplement, nicotinamide riboside (NR), to see if it improves immune system function in people with SLE. People with SLE will be asked to take the supplement or placebo for 12 weeks. Healthy control subjects will be enrolled to compare baseline blood results but will not take the supplement.

Researchers are examining genetic and physical characteristics of the small vessel disease called CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy). They are enrolling volunteers to serve as healthy controls. Compensation is provided.

Healthy volunteers 18-60 years old are needed to test an investigational drug that was developed to reduce blood pressure in the lungs. The PAH team from @NHLBI hope that this investigational study drug may be helpful in treating patients with PAH in the future.

A research study at the National Heart Lung and Blood Institute (NHLBI) is looking for pregnant women between 18 and 45 years of age who are at risk of having an infant with sickle cell disease and women who are pregnant with no risk of having an infant with sickle cell to donate their baby's cord blood. Tests and procedures provided at no cost. Travel may be reimbursed.

Researchers at the National Institutes of Health are investigating the role of Near-Infrared Spectroscopy (NIRS) technologies as a monitoring tool for measuring oxygen levels, blood flow, and the make-up of skin and muscle in patients with sickle cell disease (SCD). In this study, researchers will compare NIRS measurements in people with and without SCD.

Researchers at the National Institutes of Health (NIH) seek healthy volunteers to provide blood samples for research studies of blood vessels and immune diseases that cause clotting. In this study, investigators want to understand the basis of these diseases to facilitate the development of better treatments.

Doctors at the National Institutes of Health (NIH) seek healthy volunteers for a research study that is collecting bone marrow samples from healthy adults. Samples will be used for clinical research in the Hematology Branch and are indispensable for many research projects, including studies of normal and abnormal blood cells in the human body, blood diseases, the role of the immune system in marrow failure; and the genetic risk factors for aplastic anemia.

The National Institutes of Health (NIH) seeks healthy volunteers for a study about blood vessel stiffness. In this study, healthy volunteers will be compared with patients with rare genetic conditions that affect the blood vessels. All study-related procedures are provided at no cost and compensation is provided.