151 results
Characterization of Brain Morphology and Activity Using Functional and Anatomical MRI Contrast
Research study #00-N-0082 aims to develop improved MRI techniques for studying brain function. Information obtained will be used to develop better imaging methods that will, in turn, permit a greater understanding of normal and abnormal brain behaviors.
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NIH Tests Fecal Transplant in Chronic Granulomatous Disease-Associated Colitis
Researchers at NIH are testing a new therapy in patients diagnosed with colitis due to chronic granulomatous disease (CGD). The research aims to see if restoring the gut microbiome reduces inflammation in the colon.
Vaccine Responses in Patients with B Cell Malignancies
Research Study 000444-H investigating how well the following vaccines work in patients with CLL/SLL malignancies: SHINGRIX and influenza vaccine. If you are currently receiving treatment for your CLL/SLL (e.g. ibrutinib, acalabrutinib or venetoclax), you may be able to participate.
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A Study of Anti-Cancer Drug Abemaciclib on Brain Tumors
Researchers want to see if they can measure the amount of anti-cancer drug, Abemaciclib in a brain tumor and brain fluid after a patient has taken this drug for a few days. These findings can help explain how much drug gets into the brain and how drugs work to shrink high grade gliomas to improve outcomes for these patients.
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Observational Study of Cardiac Arrhythmias in Subjects Treated with BTK Inhibitors
Pharmacologic therapy with Bruton's tyrosine kinase (BTK) inhibitors is associated with an increased risk of heart problems like atrial fibrillation, bleeding, and high blood pressure (hypertension) which can lead to sudden death. There is currently no standard for cardiac screening or monitoring patients on BTK inhibitors. Researchers at the National Heart, Lung, and Blood Institute (NHLBI) are investigating the relationship between the development of heart problems in patients on BTKi as it relates to other variables.
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