Featured Studies

Doctors at the National Cancer Institute (NCI) are looking for volunteers with metastatic cancers, including breast, ovarian, endometrial, gastrointestinal, genitourinary, hepatobiliary, pancreatic, melanoma, non-small cell lung cancer (NSCLC), and multiple myeloma with solid masses. Potential participants will be evaluated with new immunotherapy treatments utilizing cell transfer immunotherapies in a research trial.

Investigators at the National Cancer Institute (NCI) are enrolling patients with advanced hepatocellular cancers (HCC), in a clinical trial using engineered immune cells, also known as chimeric antigen receptor T-cells or CAR-T cells. In this study, your immune T-cells are collected and modified to target Glypican-3 (GPC3), a protein marker found on the surface of HCC tumors. Researchers hope the altered cells will help identify and fight the cancer cells.

Doctors at the National Institutes of Health (NIH) are investigating new techniques needed to develop gene therapy or other treatment for certain inherited immune system diseases. If you have an inherited disease that is affecting your blood or bone marrow cell that generate blood cells, you may be eligible to participate in this research study. Participants will be screened with a medical history, physical examination and blood and urine tests.

Investigators at The National Institutes of Health (NIH) are conducting a research study to understand taste and smell alterations and how they differ in obese versus non-obese individuals.

Doctors at the National Institutes of Health (NIH) are conducting a study on patients with Clonal Cytopenia of Uncertain Significance (CCUS). Patients with CCUS have low blood counts and a normal bone marrow exam but more advanced genetic testing shows the presence of a genetic mutation that is likely causing the low counts. The study will look at CCUS and try to determine its relationship to blood cancers and heart disease. The study will also try to discover other new organs or diseases it may be linked with.

The National Institutes of Health (NIH) is conducting a research study for patients with lupus. Doctors want to learn more about the disease and are looking for what causes it, how it progresses over time, and the genetic factors that might make a person more likely to develop it. This study is open to any individual, 10 years of age or older, who meets the American College of Rheumatology's criteria for having lupus, which include symptoms and abnormal blood tests.

Cystic fibrosis (CF) is a progressive, genetic disease that causes persistent lung infections and over time limits the ability of individuals to breathe. Researchers at the National Institutes of Health (NIH) are studying the infection, disease progression, and abnormal genes responsible for cystic fibrosis to better understand the disease process and its effects on breathing.

Doctors at the National Institutes of Health are conducting a research study (92-I-0125) to learn more about the immune system and how it responds to HIV infection in blood, lymph nodes, and bone marrow. We are seeking healthy volunteers to have a lymph node biopsy to compare with patients who have HIV.

Researchers at the National Institutes of Health (NIH) are studying if low dose CT scans are as effective as regular CT scans to monitor your disease status. Very low-dose scanning uses about 1/30th the amount of radiation as a regular CT scan.