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Expanding the Scope of Infection and Inflammation Imaging: Past Lessons and Future Prospects Agenda

One-day virtual symposium set at the Clinical Center, National Institutes of Health

8:30 AM-4:30 PM, June 10th, 2021 (all times EDT)

Imaging Host-responses (8:30-10:10 AM):

Moderator: Dima Hammoud, NIH

Intro (10 min)

  • 8:40-9:00: Imaging T-cell mediated inflammation using anti-human CD3 mAb. Matthias Miederer, Mainz University
  • 9:00-9:20: Imaging immune cell populations using radiolabeled antibodies in inflammatory bowel disease. Patrick A Hughes, The University of Adelaide
  • 9:20-9:40: Tracking immune cells in CNS infections using intravital two-photon microscopy. Dorian McGavern, NINDS, NIH
  • 9:40-10:00: PET/CT Imaging of Immune Cells in a Macaque Model of Tuberculosis. Carolyn J. Anderson, University of Missouri

10:00-10:10: Discussion

Break (10:10-10:20)

Tracking the pathogen: part 1 (10:20 AM-12:00 PM):

Moderator: Swati Shah, NIH

  • 10:20-10:40: Developing bacteria-specific tracers: Bench to Bedside. Sanjay Jain, JHMI
  • 10:40-11:00: Imaging infection using bacteria-specific metabolic pathways. David Wilson, UCSF
  • 11:00-11:20: Imaging bacterial infections with d-[5-11C]-Glutamine. Xiankai Sun, University of Texas Southwestern Medical Center
  • 11:20-11:40: Imaging bacterial infection with prodrugs of 18F-PABA. Yong Li, Stony Brook University

11:40-11:50: Discussion

Lunch Break (11:50-12:30 PM)

Tracking the pathogen: part 2 (12:30-2:00 PM):

Moderator: Sanjay Jain, JHMI

  • 12:30-12:50: Bacterial infection imaging with 18F-Fluoromaltotriose. Andrei Iagaru, Stanford University
  • 12:50-1:10: Imaging bacterial and fungal infections using labeled siderophores. Milos Petrik, Palacky University Olomouc
  • 1:10-1:30: Imaging bacterial biofilm infections using conjugates of vancomycin and near-infrared fluorophores. Jan Maarten van Dijl, University Medical Center Groningen (UMCG)
  • 1:30-1:50: Imaging fungal infections using labeled antibodies. Christopher R. Thornton, University of Exeter

1:50-2:00: Discussion

Break (2:00-2:15 PM)

Imaging viral infections / High-Containment Pathogens (2:30-4:00 PM):

Moderator: Filipa Mota, JHMI

  • 2:15-2:35: Imaging HIV infection: Searching for the reservoir, Henry VanBrocklin, UCSF
  • 2:35-2:55: Molecular imaging of high consequence viral infections, Dima Hammoud, NIH
  • 2:55-3:15: Imaging Covid-19 infection in non human primates: Ian Crozier, IRF, NIAID
  • 3:15-3:35: PET imaging in SARS-CoV-2 infected hamsters: Camilo Ruiz-Bedoya, JHMI

3:35-3:45: Discussion

Wrap up (3:45-4:00 PM)