The NIH Clinical Center is the world's largest hospital entirely devoted to clinical research. It is a national resource that makes it possible to rapidly translate scientific observations and laboratory discoveries into new approaches for diagnosing, treating, and preventing disease.
Clinical research is at the heart of the Clinical Center's mission.
Over 1,600 clinical research studies are conducted at the NIH Clinical Center, including those focused on cancer, infectious diseases, blood disorders, heart disease, lung disease, alcoholism and drug abuse. Most of these studies are sponsored by the Institutes and Centers at NIH.
Here is a sample of abstracts from the clinical research conducted at the NIH Clinical Center and published in a peer reviewed medical journal this year. Links to the full text and video formats are provided if available.
2025

The Relationship Between Stiff Knee Gait Runner's Dystonia and Musculoskeletal Knee Pathology: A Case Series
Published in: Toxins (March 2025)
Runner's Dystonia (RD) is a rare movement disorder causing involuntary muscle contractions in the lower limbs during running. This condition is often overlooked or misdiagnosed due to RD patients overlapping symptomology with other conditions. Treatments to address neurological and musculoskeletal factors could improve patient outcomes. This research paves the way for personalized treatment plans and brings RD awareness to prevent long-term disability and improve quality of life.
Read the article.
Read more articles about research in the NIH Clinical Center in 2025.