Women diagnosed with polycystic ovary syndrome (PCOS) needed for a research study at the National Institutes of Health. Researchers want to learn more about how a medication may be used to help your body's insulin work better and if this can improve your overall metabolic health.
During the study you will:
- Have a medical history and physical exam
- Have four outpatient visits to include blood tests, EKG, and questionnaires
- Have four separate inpatient visits at the NIH Clinical Center lasting four days each (over three months)
- Have glucose tolerance tests, hyperinsulinemic tests, PET-CT scans, and liver ultrasounds
- Take an FDA-approved medication and placebo tablet for four-weeks each
- Receive compensation for your participation
You can participate if you:
- Are a woman between 18-40 years
- Have a body mass index (BMI) of 20-45 (calculate your BMI at https://go.usa.gov/x5My6)
- Are taking oral contraceptives
You can NOT participate if you:
- Have Type 1 or Type 2 diabetes, hypertension, heart disease, or a psychological condition
- Have been pregnant, given birth, or have been breastfeeding in the last 12 months
- Are allergic to mirabegron or a similar drug
- Drink more than two drinks per day or smoke
- Spend more than 70% of your daily hours outside
The NIH Clinical Center, America's research hospital is located in Bethesda, MD, in the Washington DC metro area on the Metro red line (Medical Center stop).
For more information:
NIH Clinical Center
Office of Patient Recruitment
800-411-1222 (refer to study 17-DK-0054)
(TTY users dial 7-1-1)
Se habla español
Email: ccopr@nih.gov
Or go online:
https://go.usa.gov/x5Mmj
Department of Health and Human Services
National Institutes of Health Clinical Center
National Institute of Diabetes and Digestive and Kidney Diseases