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Clinical Studies at NIH Clinical Center in Need of Participants

CCNews Newsletter Story

Fever, Sores, and Storms: A Child's Journey with PFAPA- New Study is Looking for Volunteers

Child in bed with caregiver taking temperatureImagine a child's world suddenly turning into a feverish landscape. One week, everything is sunshine and laughter; the next, a mysterious fever blankets them, their throat becomes a rasping desert, and angry red sores bloom in their mouth. Swollen neck glands make turning their head a chore. These puzzling episodes, like unwelcome storms, leave the child bewildered and drained.

However, unlike a random storm, PFAPA flares often return with predictable timing. This regularity is an important clue in diagnosing PFAPA.

PFAPA is the most common periodic fever syndrome in children. Researchers at the National Institute of Allergy and Infectious Diseases (NIAID), led by Dr. Manthiram, are on a quest to better understand this condition. They're seeking participants aged one month and older from anywhere in the world to join their research study.

Your participation won't require you to leave your home. You can contribute to the study from the comfort of your own home simply by sharing your child's medical records and history. In some cases, additional samples like blood, mouth swabs, saliva, or stool may be collected and sent by mail. Your participation could be a significant step towards understanding and getting better treatments for PFAPA. Compensation provided.

You can learn more online go.nih.gov/L29b0aX or call the NIH Clinical Center Office of Patient Recruitment at 1-800-411-1222 and ask for information on NIH research study 001043-I.

Malaria Study

Researcher looking through microscope in lab.In the quiet halls of the National Institute of Allergy and Infectious Diseases (NIAID), a team led by Dr. Joel Goldberg is embarking on a quest to conquer one of humanity's oldest foes: malaria.

Malaria, a major threat in the developing world is caused by a microscopic parasite spread by certain mosquitoes. Upon a single bite, this stealthy parasite infiltrates the body, leading to serious illness if not treated. But fear not! There's hope on the horizon, and you can be part of it. Imagine a world where vaccines stand guard, halting malaria transmission and shielding communities from infection. That dream is within reach, thanks to a groundbreaking clinical study at the NIAID.

NIAID is seeking volunteers aged 18-54, to join a study that aims to unlock the secrets of malaria transmission. Participants will undergo controlled infection with malaria parasites, not through mosquito bites, but through a carefully administered injection. This approach, utilizing the P. vivax species, is known to be reliably treatable.

But this isn't just any study – it's a chance to be at the forefront of scientific discovery, to contribute to the development of life-saving vaccines that will shape the future of global health. So, if you're ready to be a hero in the fight against malaria, if you're eager to join a team of dedicated researchers on a journey of discovery, then seize this opportunity! Call 866-444-2214 (TTY users dial 7-1-1) or email ccopr@nih.gov today and quote study #001970 go.nih.gov/Ol5eUL1.

Together, let's turn the tide against malaria and build a healthier, brighter future for all. Join us on this extraordinary adventure.