Rose
Lee, MD
Clinical Microbiologist
Director, Specimen Processing
Co-Director, Bacteriology
Dr. Rose Lee is a clinical microbiologist and dual-boarded adult and pediatric infectious diseases physician with a focus on developing novel diagnostics, tackling multidrug resistance, and optimizing diagnostic utilization and stewardship.
BS, Massachusetts Institute of Technology
MD, Northwestern Feinberg School of Medicine
MSPH, Johns Hopkins Bloomberg School of Public Health
Dr. Lee received her MD from Northwestern University Feinberg School of Medicine and an MSPH from the Johns Hopkins Bloomberg School of Public Health. She completed a Medicine-Pediatrics residency at University Hospitals Cleveland Medical Center and University Hospitals Rainbow Babies & Children’s, followed by fellowship training in adult and pediatric infectious diseases and clinical microbiology at Beth Israel Deaconess Medical Center and Boston Children’s Hospital.
She is board-certified in adult and pediatric infectious diseases and a diplomate of the American Board of Medical Microbiology.
In 2023, Dr. Lee joined the NIH Clinical Center, where she serves as the Director of Specimen Processing and Co-Director of Bacteriology, as well as the Program Director for the ASM CPEP Clinical Microbiology Fellowship. She is also an Infectious Diseases attending at the Clinical Center.
Her research focuses on developing and evaluating novel diagnostic technologies, including synthetic biology-based approaches, to improve infectious disease detection and management. She is also interested in diagnostic utilization and stewardship, as well as understanding and addressing multidrug resistance to optimize clinical decision-making and patient outcomes.
Lee RA. Clinical performance evaluation of the BioFire Joint Infection Panel. J Clin Microbiol. 2024;62(11):e01022-24.
Niles DT*, Lee RA*, Lamb GS, Al Dhaheri F, Boguniewicz J. Plasma cell-free metagenomic next-generation sequencing in the clinical setting for the diagnosis of infectious diseases: A systematic review and meta-analysis. Diagn Microbiol Infect Dis. 2022;105(1):115838. *Equal contribution
Lee RA, Herigon JC, Benedetti A, Pollock NR, Denkinger CM. Performance of saliva, oropharyngeal swabs, and nasal swabs for SARS-CoV-2 molecular detection: A systematic review and meta-analysis. J Clin Microbiol. 2021;59(5):e02881-20.
De Puig H*, Lee RA*, Najjar D*, Tan X*, Soenksen LR, Angenent-Mari NM, et al. Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants. Sci Adv. 2021;7(32):eabh2944. *Equal contribution
Lee RA, De Puig H, Nguyen PQ, Angenent-Mari NM, Donghia NM, McGee JP, et al. Ultrasensitive CRISPR-based diagnostic for field-applicable detection of Plasmodium species in symptomatic and asymptomatic malaria. Proc Natl Acad Sci U S A. 2020;117(41):25722-25731. doi:10.1073/pnas.2010196117
Lee RA, Al Dhaheri F, Pollock NR, Sharma TS. Assessment of the clinical utility of plasma metagenomic next-generation sequencing in a pediatric hospital population. J Clin Microbiol. 2020;58(7):e00419-20. doi:10.1128/jcm.00419-20